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Diagnostic accuracy results from included studies, with data presented to differentiate between clinicians experienced in POC LUS and inexperienced clinicians.","source_row":6.0,"source_sha256":"52795764c2fa84c293ed241e8522eda1dd06a639c405ed7892dff778377469fe","source_license":"CC BY 4.0","source_license_url":"https://creativecommons.org/licenses/by/4.0/","category":"PMC Open Access","quality_status":"ok","analysis_scope":"external_main","primary_atlas":true,"source_year":null,"tp":40.0,"fp":17.0,"fn":4.0,"tn":36.0,"sample_size":97.0,"observed_prevalence":0.4536082474226804,"sensitivity":0.9090909090909091,"specificity":0.6792452830188679,"ppv_observed":0.7017543859649122,"npv_observed":0.9,"youden_j":0.588336192109777,"lr_positive":2.8342245989304806,"lr_negative":0.1338383838383839,"diagnostic_odds_ratio":21.176470588235293,"baseline_entropy_bits_observed":0.9937811379408326,"conditional_entropy_bits_observed":0.7100057984970234,"information_bits_observed":0.28377533944380917,"information_fraction_observed":0.28555114261054176,"import_status":"included","import_notes":"Rates and information metrics recomputed from source counts.","provenance_hash":"1e7c969a98ee"},{"id":"study:pmc-open-access:pmc-pmc11563508:fda24a7c42dc:dc5440c1dd8d:3d2a3ef9c8b7","collection_id":"individual-studies","evidence_level":"individual_study","label":"Overall structured 2 x 2 data","test_or_feature":"Overall structured 2 x 2 data","target_condition":"Diagnostic accuracy of point-of-care lung ultrasound for community-acquired pneumonia in children in ambulatory settings: A systematic review and meta-analysis","citation":"Samson et al. 28","review_title":"Diagnostic accuracy of point-of-care lung ultrasound for community-acquired pneumonia in children in ambulatory settings: A systematic review and meta-analysis","review_id":"PMC:PMC11563508","group_id":"pmc open access:PMC11563508:table3-1742271X241289726:table-3-diagnostic-accuracy-results-from-included-studies-with-data-presented-to:1:overall","study_id":"Samson et al. 28","source":"PMC Open Access","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11563508/","source_record_id":"PMC:PMC11563508:pmc open access:PMC11563508:table3-1742271X241289726:table-3-diagnostic-accuracy-results-from-included-studies-with-data-presented-to:1:overall:Samson et al. 28","source_file":"PMC11563508.xml","source_sheet":"Table 3. 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[ 22 ]","review_title":"Diagnostic Accuracy of Cerebrospinal Fluid (CSF) Adenosine Deaminase (ADA) for Tuberculous Meningitis (TBM) in Adults: A Systematic Review and Meta-Analysis","review_id":"PMC:PMC10316459","group_id":"pmc open access:PMC10316459:TAB2:table-2-characteristics-of-studies-b-bacteriology-cd-clinical-diagnosis-cect-con:1:overall","study_id":"Krishnaswamy et al. [ 22 ]","source":"PMC Open Access","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10316459/","source_record_id":"PMC:PMC10316459:pmc open access:PMC10316459:TAB2:table-2-characteristics-of-studies-b-bacteriology-cd-clinical-diagnosis-cect-con:1:overall:Krishnaswamy et al. [ 22 ]","source_file":"PMC10316459.xml","source_sheet":"Table 2 Characteristics of studies. 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ICU intensive care unit, SIRS systemic inflammatory response syndrome, TP true positive, FP false positive, TN true negative, FN false negative, ED emergency department, AuROC area under curve, HAP hospital-acquired pneumonia, NR not reported. * within which 15 patients did not have sample available for analysis, † A total of 117 patients were determined with infection, within which 96 patients were bacterial infection, 16 patients were viral infection and five patients were parasite infection. Soluble TREM-1 was used to diagnose bacterial infections in SIRS","source_row":8.0,"source_sha256":"eb686cc4c1c4f8991f9ada2adfe8f91935e38b8d95884db1b0acf2e9747c64f3","source_license":"CC BY 4.0","source_license_url":"http://creativecommons.org/licenses/by/4.0/","category":"PMC Open Access","quality_status":"ok","analysis_scope":"external_main","primary_atlas":true,"source_year":2004,"tp":45.0,"fp":3.0,"fn":2.0,"tn":26.0,"sample_size":76.0,"observed_prevalence":0.618421052631579,"sensitivity":0.9574468085106383,"specificity":0.896551724137931,"ppv_observed":0.9375,"npv_observed":0.9285714285714286,"youden_j":0.8539985326485695,"lr_positive":9.255319148936172,"lr_negative":0.047463175122749536,"diagnostic_odds_ratio":195.0,"baseline_entropy_bits_observed":0.9591495543968942,"conditional_entropy_bits_observed":0.34979510978369976,"information_bits_observed":0.6093544446131944,"information_fraction_observed":0.6353070194526148,"import_status":"included","import_notes":"Rates and information metrics recomputed from source counts.","provenance_hash":"24b57c5453fd"},{"id":"study:pmc-open-access:pmc-pmc6958609:bec11627545d:2b2a85441892:fe5e86a0f12e","collection_id":"individual-studies","evidence_level":"individual_study","label":"Overall structured 2 x 2 data","test_or_feature":"Overall structured 2 x 2 data","target_condition":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","citation":"Gibot S et al., 2012 [ 21 ]","review_title":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","review_id":"PMC:PMC6958609","group_id":"pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall","study_id":"Gibot S et al., 2012 [ 21 ]","source":"PMC Open Access","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6958609/","source_record_id":"PMC:PMC6958609:pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall:Gibot S et al., 2012 [ 21 ]","source_file":"PMC6958609.xml","source_sheet":"Table 1 Characteristics of the included studies. ICU intensive care unit, SIRS systemic inflammatory response syndrome, TP true positive, FP false positive, TN true negative, FN false negative, ED emergency department, AuROC area under curve, HAP hospital-acquired pneumonia, NR not reported. * within which 15 patients did not have sample available for analysis, † A total of 117 patients were determined with infection, within which 96 patients were bacterial infection, 16 patients were viral infection and five patients were parasite infection. Soluble TREM-1 was used to diagnose bacterial infections in SIRS","source_row":9.0,"source_sha256":"eb686cc4c1c4f8991f9ada2adfe8f91935e38b8d95884db1b0acf2e9747c64f3","source_license":"CC BY 4.0","source_license_url":"http://creativecommons.org/licenses/by/4.0/","category":"PMC Open Access","quality_status":"ok","analysis_scope":"external_main","primary_atlas":true,"source_year":2012,"tp":82.0,"fp":20.0,"fn":72.0,"tn":126.0,"sample_size":300.0,"observed_prevalence":0.5133333333333333,"sensitivity":0.5324675324675324,"specificity":0.863013698630137,"ppv_observed":0.803921568627451,"npv_observed":0.6363636363636364,"youden_j":0.3954812310976694,"lr_positive":3.887012987012987,"lr_negative":0.5417439703153989,"diagnostic_odds_ratio":7.175,"baseline_entropy_bits_observed":0.9994869809508898,"conditional_entropy_bits_observed":0.8669009963852974,"information_bits_observed":0.13258598456559245,"information_fraction_observed":0.132654038614343,"import_status":"included","import_notes":"Rates and information metrics recomputed from source counts.","provenance_hash":"a34b94f435f6"},{"id":"study:pmc-open-access:pmc-pmc6958609:bec11627545d:277f168dc6b4:51b7e6c31cc2","collection_id":"individual-studies","evidence_level":"individual_study","label":"Overall structured 2 x 2 data","test_or_feature":"Overall structured 2 x 2 data","target_condition":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","citation":"Halim B et al., 2015 [ 22 ]","review_title":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","review_id":"PMC:PMC6958609","group_id":"pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall","study_id":"Halim B et al., 2015 [ 22 ]","source":"PMC Open Access","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6958609/","source_record_id":"PMC:PMC6958609:pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall:Halim B et al., 2015 [ 22 ]","source_file":"PMC6958609.xml","source_sheet":"Table 1 Characteristics of the included studies. ICU intensive care unit, SIRS systemic inflammatory response syndrome, TP true positive, FP false positive, TN true negative, FN false negative, ED emergency department, AuROC area under curve, HAP hospital-acquired pneumonia, NR not reported. * within which 15 patients did not have sample available for analysis, † A total of 117 patients were determined with infection, within which 96 patients were bacterial infection, 16 patients were viral infection and five patients were parasite infection. Soluble TREM-1 was used to diagnose bacterial infections in SIRS","source_row":10.0,"source_sha256":"eb686cc4c1c4f8991f9ada2adfe8f91935e38b8d95884db1b0acf2e9747c64f3","source_license":"CC BY 4.0","source_license_url":"http://creativecommons.org/licenses/by/4.0/","category":"PMC Open Access","quality_status":"ok","analysis_scope":"external_main","primary_atlas":true,"source_year":2015,"tp":27.0,"fp":11.0,"fn":6.0,"tn":30.0,"sample_size":74.0,"observed_prevalence":0.44594594594594594,"sensitivity":0.8181818181818182,"specificity":0.7317073170731707,"ppv_observed":0.7105263157894737,"npv_observed":0.8333333333333334,"youden_j":0.5498891352549888,"lr_positive":3.049586776859504,"lr_negative":0.24848484848484842,"diagnostic_odds_ratio":12.272727272727273,"baseline_entropy_bits_observed":0.9915528503834039,"conditional_entropy_bits_observed":0.7619775990104469,"information_bits_observed":0.22957525137295698,"information_fraction_observed":0.23153102861253141,"import_status":"included","import_notes":"Rates and information metrics recomputed from source counts.","provenance_hash":"b64826ac9378"},{"id":"study:pmc-open-access:pmc-pmc6958609:bec11627545d:adcb860be88c:0b0e7050559d","collection_id":"individual-studies","evidence_level":"individual_study","label":"Overall structured 2 x 2 data","test_or_feature":"Overall structured 2 x 2 data","target_condition":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","citation":"Kofoed K et al., 2007 [ 23 ]","review_title":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","review_id":"PMC:PMC6958609","group_id":"pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall","study_id":"Kofoed K et al., 2007 [ 23 ]","source":"PMC Open Access","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6958609/","source_record_id":"PMC:PMC6958609:pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall:Kofoed K et al., 2007 [ 23 ]","source_file":"PMC6958609.xml","source_sheet":"Table 1 Characteristics of the included studies. ICU intensive care unit, SIRS systemic inflammatory response syndrome, TP true positive, FP false positive, TN true negative, FN false negative, ED emergency department, AuROC area under curve, HAP hospital-acquired pneumonia, NR not reported. * within which 15 patients did not have sample available for analysis, † A total of 117 patients were determined with infection, within which 96 patients were bacterial infection, 16 patients were viral infection and five patients were parasite infection. Soluble TREM-1 was used to diagnose bacterial infections in SIRS","source_row":11.0,"source_sha256":"eb686cc4c1c4f8991f9ada2adfe8f91935e38b8d95884db1b0acf2e9747c64f3","source_license":"CC BY 4.0","source_license_url":"http://creativecommons.org/licenses/by/4.0/","category":"PMC Open Access","quality_status":"ok","analysis_scope":"external_main","primary_atlas":true,"source_year":2007,"tp":79.0,"fp":33.0,"fn":17.0,"tn":22.0,"sample_size":151.0,"observed_prevalence":0.6357615894039735,"sensitivity":0.8229166666666666,"specificity":0.4,"ppv_observed":0.7053571428571429,"npv_observed":0.5641025641025641,"youden_j":0.22291666666666665,"lr_positive":1.3715277777777777,"lr_negative":0.4427083333333334,"diagnostic_odds_ratio":3.0980392156862746,"baseline_entropy_bits_observed":0.9461452405629116,"conditional_entropy_bits_observed":0.9039495950329994,"information_bits_observed":0.042195645529912174,"information_fraction_observed":0.044597429359585175,"import_status":"included","import_notes":"Rates and information metrics recomputed from source counts.","provenance_hash":"71cc7adec711"},{"id":"study:pmc-open-access:pmc-pmc6958609:bec11627545d:c0de07a3d5c3:c15ae052e04b","collection_id":"individual-studies","evidence_level":"individual_study","label":"Overall structured 2 x 2 data","test_or_feature":"Overall structured 2 x 2 data","target_condition":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","citation":"Latour-Perez J et al., 2010 [ 24 ]","review_title":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","review_id":"PMC:PMC6958609","group_id":"pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall","study_id":"Latour-Perez J et al., 2010 [ 24 ]","source":"PMC Open Access","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6958609/","source_record_id":"PMC:PMC6958609:pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall:Latour-Perez J et al., 2010 [ 24 ]","source_file":"PMC6958609.xml","source_sheet":"Table 1 Characteristics of the included studies. ICU intensive care unit, SIRS systemic inflammatory response syndrome, TP true positive, FP false positive, TN true negative, FN false negative, ED emergency department, AuROC area under curve, HAP hospital-acquired pneumonia, NR not reported. * within which 15 patients did not have sample available for analysis, † A total of 117 patients were determined with infection, within which 96 patients were bacterial infection, 16 patients were viral infection and five patients were parasite infection. 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ICU intensive care unit, SIRS systemic inflammatory response syndrome, TP true positive, FP false positive, TN true negative, FN false negative, ED emergency department, AuROC area under curve, HAP hospital-acquired pneumonia, NR not reported. * within which 15 patients did not have sample available for analysis, † A total of 117 patients were determined with infection, within which 96 patients were bacterial infection, 16 patients were viral infection and five patients were parasite infection. Soluble TREM-1 was used to diagnose bacterial infections in SIRS","source_row":13.0,"source_sha256":"eb686cc4c1c4f8991f9ada2adfe8f91935e38b8d95884db1b0acf2e9747c64f3","source_license":"CC BY 4.0","source_license_url":"http://creativecommons.org/licenses/by/4.0/","category":"PMC Open Access","quality_status":"ok","analysis_scope":"external_main","primary_atlas":true,"source_year":2013,"tp":30.0,"fp":3.0,"fn":8.0,"tn":11.0,"sample_size":52.0,"observed_prevalence":0.7307692307692307,"sensitivity":0.7894736842105263,"specificity":0.7857142857142857,"ppv_observed":0.9090909090909091,"npv_observed":0.5789473684210527,"youden_j":0.5751879699248121,"lr_positive":3.6842105263157894,"lr_negative":0.2679425837320574,"diagnostic_odds_ratio":13.75,"baseline_entropy_bits_observed":0.8403586716091171,"conditional_entropy_bits_observed":0.6376976061313038,"information_bits_observed":0.20266106547781337,"information_fraction_observed":0.24116020019137585,"import_status":"included","import_notes":"Rates and information metrics recomputed from source counts.","provenance_hash":"f15732769b9a"},{"id":"study:pmc-open-access:pmc-pmc6958609:bec11627545d:895c6f5fd9c8:02093be18a4c","collection_id":"individual-studies","evidence_level":"individual_study","label":"Overall structured 2 x 2 data","test_or_feature":"Overall structured 2 x 2 data","target_condition":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","citation":"Li Z et al., 2016 [ 26 ]","review_title":"Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis","review_id":"PMC:PMC6958609","group_id":"pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall","study_id":"Li Z et al., 2016 [ 26 ]","source":"PMC Open Access","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6958609/","source_record_id":"PMC:PMC6958609:pmc open access:PMC6958609:Tab1:table-1-characteristics-of-the-included-studies-icu-intensive-care-unit-sirs-sys:1:overall:Li Z et al., 2016 [ 26 ]","source_file":"PMC6958609.xml","source_sheet":"Table 1 Characteristics of the included studies. ICU intensive care unit, SIRS systemic inflammatory response syndrome, TP true positive, FP false positive, TN true negative, FN false negative, ED emergency department, AuROC area under curve, HAP hospital-acquired pneumonia, NR not reported. * within which 15 patients did not have sample available for analysis, † A total of 117 patients were determined with infection, within which 96 patients were bacterial infection, 16 patients were viral infection and five patients were parasite infection. 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ICU intensive care unit, SIRS systemic inflammatory response syndrome, TP true positive, FP false positive, TN true negative, FN false negative, ED emergency department, AuROC area under curve, HAP hospital-acquired pneumonia, NR not reported. * within which 15 patients did not have sample available for analysis, † A total of 117 patients were determined with infection, within which 96 patients were bacterial infection, 16 patients were viral infection and five patients were parasite infection. 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